Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 5/20 | 0.70 |
| ▸ | CDC25B | P30305 | 2/20 | 0.70 |
| ▸ | NPC1L1 | Q9UHC9 | 4/20 | 0.59 |
| ▸ | USP2 | O75604 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.55 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | OSBP | P22059 | 1/20 | 0.53 |
| ▸ | RORC | P51449 | 1/20 | 0.53 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.53 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11377212 | 1.00 | CDC25A (0.70) | CDC25ACDC25BNPC1L1USP2LMNA | |
| SCHEMBL18844064 | 1.00 | CDC25A (0.70) | CDC25ACDC25BNPC1L1USP2LMNA | |
| SCHEMBL28099715 | 1.00 | CDC25A (0.70) | CDC25ACDC25BNPC1L1USP2LMNA | |
| SCHEMBL26642192 | 0.90 | CDC25A (0.56) | CDC25ACDC25BNPC1L1USP2LMNA | |
| SCHEMBL9951528 | 0.90 | CDC25A (0.56) | CDC25ACDC25BNPC1L1USP2LMNA | |
| SCHEMBL6560663 | 0.89 | CDC25A (0.57) | CDC25ACDC25BNPC1L1USP2LMNA | |
| SCHEMBL29760287 | 0.88 | CDC25A (0.54) | CDC25ACDC25BNPC1L1USP2LMNA | |
| SCHEMBL8475208 | 0.87 | CYP2D6 (0.55) | CDC25ACDC25BNPC1L1USP2LMNA | |
| SCHEMBL22472242 | 0.87 | GPBAR1 (0.72) | CDC25ACDC25BNPC1L1USP2LMNA | |
| SCHEMBL5341062 | 0.87 | GPBAR1 (0.72) | CDC25ACDC25BNPC1L1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2654779-A1 | LIPOSOMAL FORMULATION OF NONGLYCOSIDIC CERAMIDES AND USES THEREOF | Ludwig Institute for Cancer Research, Ltd. (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012088414-A1 | LIPOSOMAL FORMULATION OF NONGLYCOSIDIC CERAMIDES AND USES THEREOF | LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (US) | 2012-06-28 | — | — | WO | disclosed |
| US-4252719-A | REMOVAL OF A TERTIARY HYDROGEN FROM A 5-A-STEROID BY CHLORINATING THE STEROID BEING FIRST ESTERIFIED BY AN IODOARYL-CONTAINING ESTERIFICATION AGENT | RESEARCH CORPORATION (US) | 1981-02-24 | — | — | US | disclosed |