Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.56 |
| ▸ | CDC25B | P30305 | 1/20 | 0.56 |
| ▸ | OSBP | P22059 | 2/20 | 0.56 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.56 |
| ▸ | RORC | P51449 | 1/20 | 0.56 |
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | GPR183 | P32249 | 2/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.48 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.47 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9951528 | 1.00 | CDC25A (0.56) | CDC25ACDC25BOSBPNR1H3RORC | |
| SCHEMBL11377212 | 0.90 | CDC25A (0.70) | CDC25ACDC25BOSBPRORCGPBAR1 | |
| SCHEMBL28099715 | 0.90 | CDC25A (0.70) | CDC25ACDC25BOSBPRORCGPBAR1 | |
| SCHEMBL9952544 | 0.90 | CDC25A (0.70) | CDC25ACDC25BOSBPRORCGPBAR1 | |
| SCHEMBL18844064 | 0.90 | CDC25A (0.70) | CDC25ACDC25BOSBPRORCGPBAR1 | |
| SCHEMBL3231117 | 0.89 | OSBP (0.52) | CDC25ACDC25BOSBPNR1H3RORC | |
| SCHEMBL13076838 | 0.88 | GPBAR1 (0.68) | OSBPNR1H3RORCGPBAR1MAPT | |
| SCHEMBL29760287 | 0.85 | CDC25A (0.54) | CDC25ACDC25BOSBPGPBAR1MAPT | |
| SCHEMBL133953 | 0.83 | EPHA2 (0.68) | CDC25AOSBPNR1H3RORCGPBAR1 | |
| SCHEMBL17912309 | 0.83 | EPHA2 (0.68) | CDC25AOSBPNR1H3RORCGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250319190-A1 | APOE LIPOPROTEIN SYSTEMS | KISBEE THERAPEUTICS INC (US) | 2025-10-16 | — | — | US | disclosed |
| EP-4522646-A2 | APOE LIPOPROTEIN SYSTEMS | Kisbee Therapeutics, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220387-A2 | APOE LIPOPROTEIN SYSTEMS | KISBEE THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250319190-A1 | APOE LIPOPROTEIN SYSTEMS | APOB, APOL1, LDLR | CDC25A 4615/4885CDC25B 4638/4885OSBP 140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.