Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY10 | O00398 | 15/20 | 0.56 |
| ▸ | GPR34 | Q9UPC5 | 9/20 | 0.56 |
| ▸ | GPR174 | Q9BXC1 | 7/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16293534 | 1.00 | P2RY10 (0.56) | P2RY10GPR34GPR174 | |
| SCHEMBL162609 | 1.00 | P2RY10 (0.56) | P2RY10GPR34GPR174 | |
| SCHEMBL16294197 | 1.00 | P2RY10 (0.56) | P2RY10GPR34GPR174 | |
| SCHEMBL3051352 | 0.94 | P2RY10 (0.61) | P2RY10GPR34GPR174 | |
| SCHEMBL479757 | 0.91 | P2RY10 (0.58) | P2RY10GPR34GPR174 | |
| SCHEMBL29728687 | 0.86 | KDM4E (0.47) | P2RY10GPR34GPR174 | |
| SCHEMBL30063078 | 0.86 | KDM4E (0.47) | P2RY10GPR34GPR174 | |
| SCHEMBL28207261 | 0.86 | KDM4E (0.47) | P2RY10GPR34GPR174 | |
| SCHEMBL7455157 | 0.84 | P2RY10 (0.49) | P2RY10GPR34GPR174 | |
| SCHEMBL226745 | 0.83 | PLA2G2C (0.43) | P2RY10GPR34GPR174 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2654779-A1 | LIPOSOMAL FORMULATION OF NONGLYCOSIDIC CERAMIDES AND USES THEREOF | Ludwig Institute for Cancer Research, Ltd. (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012088414-A1 | LIPOSOMAL FORMULATION OF NONGLYCOSIDIC CERAMIDES AND USES THEREOF | LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (US) | 2012-06-28 | — | — | WO | disclosed |