Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY10 | O00398 | 11/20 | 0.49 |
| ▸ | GPR174 | Q9BXC1 | 5/20 | 0.49 |
| ▸ | GPR34 | Q9UPC5 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3051352 | 0.90 | P2RY10 (0.61) | P2RY10GPR174GPR34 | |
| SCHEMBL479757 | 0.88 | P2RY10 (0.58) | P2RY10GPR174GPR34 | |
| SCHEMBL16294197 | 0.84 | P2RY10 (0.56) | P2RY10GPR174GPR34 | |
| SCHEMBL16293534 | 0.84 | P2RY10 (0.56) | P2RY10GPR174GPR34 | |
| SCHEMBL9952582 | 0.84 | P2RY10 (0.56) | P2RY10GPR174GPR34 | |
| SCHEMBL162609 | 0.84 | P2RY10 (0.56) | P2RY10GPR174GPR34 | |
| SCHEMBL7571747 | 0.83 | P2RY10 (0.44) | P2RY10GPR174GPR34 | |
| SCHEMBL969822 | 0.83 | P2RY10 (0.44) | P2RY10GPR174GPR34 | |
| SCHEMBL18262003 | 0.83 | P2RY10 (0.44) | P2RY10GPR174GPR34 | |
| SCHEMBL7570925 | 0.81 | S1PR1 (0.47) | P2RY10GPR34 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925059-A4 | PROTEIN-LIPID VESICLES AND AUTOGENOUS VACCINE COMPRISING THE SAME | ALBANY MEDICAL COLLEGE (US) | 2002-03-27 | — | — | EP | disclosed |
| US-6165502-A | Protein-lipid vesicles and autogenous vaccine comprising the same | ALBANY MEDICAL COLLEGE (US) | 2000-12-26 | — | — | US | disclosed |
| EP-0925059-A1 | PROTEIN-LIPID VESICLES AND AUTOGENOUS VACCINE COMPRISING THE SAME | ALBANY MEDICAL COLLEGE (US) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998010749-A1 | PROTEIN-LIPID VESICLES AND AUTOGENOUS VACCINE COMPRISING THE SAME | ALBANY MEDICAL COLLEGE (US) | 1998-03-19 | — | — | WO | disclosed |