SCHEMBL9952680

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18250938	0.90	POLB (0.41)	RXFP1HSD17B10MAPK1ALOX15ALDH1A1
	SCHEMBL9952069	0.88	HSD17B10 (0.50)	RXFP1HSD17B10MAPK1ALOX15ALDH1A1
	SCHEMBL9952288	0.86	RXFP1 (0.48)	RXFP1HSD17B10MAPK1ALOX15ALDH1A1
	SCHEMBL9952580	0.84	RXFP1 (0.46)	RXFP1HSD17B10MAPK1ALOX15ALDH1A1
	SCHEMBL10281011	0.84	RXFP1 (0.46)	RXFP1HSD17B10MAPK1ALOX15ALDH1A1
	SCHEMBL9952720	0.81	RXFP1 (0.43)	RXFP1HSD17B10MAPK1ALOX15ALDH1A1
	SCHEMBL16667115	0.80	MAPK1 (0.55)	HSD17B10MAPK1ALOX15ALDH1A1HPGD
	SCHEMBL9952891	0.79	RXFP1 (0.52)	RXFP1HSD17B10MAPK1ALOX15ALDH1A1
	SCHEMBL17008991	0.77	RXFP1 (0.52)	RXFP1HSD17B10MAPK1ALOX15ALDH1A1
	SCHEMBL12775057	0.76	HSD17B10 (0.43)	RXFP1HSD17B10MAPK1ALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.