Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.50 |
| ▸ | MTOR | P42345 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | AXL | P30530 | 2/20 | 0.50 |
| ▸ | PI4KA | P42356 | 3/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30181104 | 0.86 | SLC22A12 (0.64) | SLC22A12PIK3CAPOLBACLYALDH1A1 | |
| SCHEMBL14247317 | 0.82 | HTT (0.54) | SLC22A12LMNAALDH1A1 | |
| SCHEMBL25407193 | 0.81 | SLC22A12 (0.55) | SLC22A12PIK3CAPOLBACLYALDH1A1 | |
| SCHEMBL30902109 | 0.81 | PI4KA (0.53) | PIK3CAMTORPOLBPI4KAPIK3CG | |
| SCHEMBL9953017 | 0.81 | PI4KA (0.53) | PIK3CAMTORPOLBPI4KAPIK3CG | |
| SCHEMBL30504937 | 0.81 | SLC22A12 (0.55) | SLC22A12PIK3CAPOLBACLYALDH1A1 | |
| SCHEMBL9955040 | 0.78 | PIK3CG (0.51) | PIK3CAMTORPOLBPI4KAPIK3CG | |
| SCHEMBL9954267 | 0.74 | SLC22A12 (0.55) | SLC22A12PIK3CAPOLBPIK3CGALDH1A1 | |
| SCHEMBL12459539 | 0.74 | TSHR (0.54) | POLBAXLLMNAACLYTSHR | |
| SCHEMBL21545956 | 0.74 | DYRK1A (0.52) | PIK3CAPOLBPIK3CGLMNAACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |