Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 8/20 | 0.51 |
| ▸ | PI4KA | P42356 | 7/20 | 0.51 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.47 |
| ▸ | MTOR | P42345 | 5/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.46 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.46 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.46 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.46 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.46 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25230896 | 0.87 | PIK3CA (0.56) | PIK3CGPI4KAPIK3C3PIK3CAMTOR | |
| SCHEMBL29536997 | 0.87 | PIK3CA (0.56) | PIK3CGPI4KAPIK3C3PIK3CAMTOR | |
| SCHEMBL789782 | 0.83 | LMNA (0.55) | PIK3CGPI4KAPIK3C3POLBPIK3CA | |
| SCHEMBL9953017 | 0.83 | PI4KA (0.53) | PIK3CGPI4KAPIK3C3POLBPIK3CA | |
| SCHEMBL30902109 | 0.83 | PI4KA (0.53) | PIK3CGPI4KAPIK3C3POLBPIK3CA | |
| SCHEMBL14247235 | 0.78 | PIK3CG (0.53) | PIK3CGPIK3C3PIK3CAPIK3R1PIK3CD | |
| SCHEMBL9952833 | 0.78 | SLC22A12 (0.54) | PIK3CGPI4KAPIK3C3POLBPIK3CA | |
| SCHEMBL16926674 | 0.77 | PIK3C3 (0.58) | PIK3C3PIK3CAMTOR | |
| SCHEMBL9953720 | 0.76 | ALPL (0.62) | PIK3CGPI4KAPIK3C3POLBPIK3CA | |
| SCHEMBL16990857 | 0.75 | PIK3C3 (0.86) | PIK3C3PIK3CAPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |