Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20472365 | 0.89 | HSD17B10 (0.41) | HSD17B10POLBTDP1LCKFYN | |
| SCHEMBL14931958 | 0.86 | HSD17B10 (0.51) | HSD17B10POLBTDP1LCKFYN | |
| SCHEMBL2431761 | 0.85 | GAA (0.54) | KDM4EALDH1A1HPGDGAAL3MBTL1 | |
| SCHEMBL3448712 | 0.82 | CNR1 (0.41) | HSD17B10LCKFYNKDM4EALDH1A1 | |
| SCHEMBL30468364 | 0.80 | ALDH1A1 (0.49) | HSD17B10LCKFYNKDM4EALDH1A1 | |
| SCHEMBL20472500 | 0.80 | ALDH1A1 (0.49) | HSD17B10LCKFYNKDM4EALDH1A1 | |
| SCHEMBL31368889 | 0.79 | TDP1 (0.49) | HSD17B10POLBTDP1KDM4EALDH1A1 | |
| SCHEMBL7810927 | 0.79 | POLB (0.45) | HSD17B10POLBTDP1LCKFYN | |
| SCHEMBL2437655 | 0.77 | AKR1C4 (0.41) | HSD17B10LCKFYNKDM4EALDH1A1 | |
| SCHEMBL30483667 | 0.77 | AKR1C4 (0.41) | HSD17B10LCKFYNKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520423-B | Aminotriazolopyridines as kinase inhibitors | 百时美施贵宝公司 | 2022-08-23 | — | — | CN | disclosed |
| WO-2018148626-A1 | AMINOTRIAZOLOPYRIDINES AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-08-16 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |