SCHEMBL9952985 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	CYP1A2	P05177	1/20	0.43

▸	TYMS	P04818	8/20	0.39

▸	PARP4	Q9UKK3	2/20	0.35

▸	FABP6	P51161	1/20	0.35

▸	PNP	P00491	1/20	0.34

▸	CYP3A4	P08684	1/20	0.34

▸	BLM	P54132	1/20	0.34

▸	FGFR1	P11362	1/20	0.33

▸	FGFR2	P21802	1/20	0.33

▸	BACE1	P56817	1/20	0.32

▸	XDH	P47989	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL10289344	0.74	CYP1A2 (0.54)	CYP1A2TYMSPARP4PNP
SCHEMBL9953662	0.70	TYMS (0.51)	TYMSPNPCYP3A4BLM
SCHEMBL14007390	0.68	CYP1A2 (0.43)	CYP1A2PARP4
SCHEMBL18088265	0.68	LMNA (0.44)	CYP1A2TYMSFGFR1FGFR2XDH
SCHEMBL23117477	0.67	MAPT (0.46)	CYP1A2
SCHEMBL2906293	0.67	F2 (0.37)	PARP4
SCHEMBL24629146	0.66	CYP3A4 (0.42)	CYP1A2TYMSFABP6PNPCYP3A4
SCHEMBL13425992	0.64	ABCB1 (0.72)	CYP1A2
SCHEMBL23520602	0.63	PARP1 (0.70)	CYP1A2TYMSPARP4
SCHEMBL8258156	0.62	PARP4 (0.38)	PARP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2012087938-A1	QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS	GLAXOSMITHKLINE LLC (US)	2012-06-28	—	—	WO	disclosed