Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2301535 | 0.80 | MAOB (0.58) | MAOBADORA2BMAPTNPC1RAB9A | |
| SCHEMBL8761733 | 0.75 | MAOB (0.61) | MAOBADORA2BMAPTNPC1RAB9A | |
| SCHEMBL2123943 | 0.74 | EED (0.41) | MAOBHPGDHSD17B10MAOAALDH1A1 | |
| SCHEMBL70456 | 0.73 | MAOB (0.76) | MAOBADORA2BMAPTNPC1RAB9A | |
| SCHEMBL31314554 | 0.73 | MAOB (0.50) | MAOBADORA2BMAPTNPC1RAB9A | |
| SCHEMBL5158204 | 0.73 | MAOB (0.50) | MAOBADORA2BMAPTNPC1RAB9A | |
| SCHEMBL1299217 | 0.72 | MAOB (0.58) | MAOBADORA2BMAPTNPC1RAB9A | |
| SCHEMBL13134176 | 0.72 | MAOB (0.49) | MAOBADORA2BMAPTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL87683 | 0.72 | MAOB (0.73) | MAOBADORA2BMAPTNPC1RAB9A | |
| SCHEMBL13655497 | 0.72 | MAOB (0.62) | MAOBADORA2BMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106986862-A | Hepatitis c inhibitor and application thereof | ABBVIE 公司 | 2017-07-28 | — | — | CN | disclosed |
| CN-103649079-B | Hepatitis c inhibitor and application thereof | ABBVIE 公司 | 2016-11-16 | — | — | CN | disclosed |
| EP-2655362-A1 | HEPATITIS C INHIBITORS AND USES THEREOF | Abbvie Inc. (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012087833-A1 | HEPATITIS C INHIBITORS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2012-06-28 | — | — | WO | disclosed |