Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | BLM | P54132 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | NQO2 | P16083 | 10/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17066129 | 0.84 | RAB9A (0.40) | RAB9AKMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL7173382 | 0.73 | NQO2 (0.62) | RAB9AKMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL28429350 | 0.72 | MAPT (0.47) | RAB9AKMT2AMAPTPOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL6265381 | 0.71 | NQO2 (0.59) | RAB9AKMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL24702675 | 0.71 | KMT2A (0.50) | RAB9AKMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL9953832 | 0.71 | MAPT (0.40) | RAB9AKMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL1186316 | 0.70 | HPGD (0.50) | RAB9AKMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL31447451 | 0.70 | NQO2 (0.42) | RAB9AKMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL20915022 | 0.70 | NQO2 (0.42) | RAB9AKMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL13818412 | 0.69 | NQO2 (0.56) | RAB9AKMT2AMAPTPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655334-A1 | COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES | Eutropics Pharmaceuticals, Inc. (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012088438-A1 | COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES | EUTROPICS PHARMACEUTICALS, INC. (US) | 2012-06-28 | — | — | WO | disclosed |