Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TTR | P02766 | 1/20 | 0.64 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | PGR | P06401 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.64 |
| ▸ | AR | P10275 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29656832 | 1.00 | HPGD (0.64) | HPGDMEN1MAPTKMT2AUSP2 | |
| Hydrochloric Acid SCHEMBL15352266 | 0.98 | HPGD (0.62) | HPGDMEN1MAPTKMT2AUSP2 | |
| SCHEMBL11080512 | 0.84 | MAPT (0.51) | HPGDMEN1MAPTKMT2AUSP2 | |
| Benzene SCHEMBL27265959 | 0.84 | TSHR (0.61) | HPGDMEN1MAPTKMT2AUSP2 | |
| SCHEMBL756585 | 0.84 | TSHR (0.61) | HPGDMEN1MAPTKMT2AUSP2 | |
| SCHEMBL27703149 | 0.84 | TSHR (0.61) | HPGDMEN1MAPTKMT2AUSP2 | |
| SCHEMBL4631526 | 0.83 | MAPT (0.51) | HPGDMEN1MAPTKMT2AUSP2 | |
| SCHEMBL108670 | 0.83 | ALDH1A1 (0.52) | HPGDMEN1MAPTKMT2AUSP2 | |
| SCHEMBL706359 | 0.83 | MAPT (0.50) | HPGDMEN1MAPTKMT2AUSP2 | |
| SCHEMBL4450233 | 0.83 | MAPT (0.50) | HPGDMEN1MAPTKMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 595 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164940-A | Preparation method of phthalide | 江苏盈科工程设计研究有限公司 | 2024-06-11 | — | — | CN | claimed |
| CN-112876403-B | Preparation method of apremilast impurity | 成都摩尔生物医药有限公司 | 2022-10-21 | — | — | CN | claimed |
| CN-112876403-A | Preparation method of apremilast impurity | 成都摩尔生物医药有限公司 | 2021-06-01 | — | — | CN | claimed |
| EP-3551633-B1 | SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | LEO PHARMA AS (DK) | 2021-03-31 | — | — | EP | claimed |
| CN-106946685-B | Preparation method of 2-methyl-3-methoxybenzoic acid and intermediate thereof | 江苏联化科技有限公司 | 2020-06-23 | — | — | CN | claimed |
| EP-3551633-A1 | SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | Leo Pharma A/S (DK) | 2019-10-16 | — | — | EP | claimed |
| WO-2018108230-A1 | SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | LEO PHARMA A/S (DK) | 2018-06-21 | — | — | WO | claimed |
| CN-106946685-A | The preparation method of 2- methyl -3- methoxy benzoic acids and its intermediate | 江苏联化科技有限公司 | 2017-07-14 | — | — | CN | claimed |
| US-8569195-B2 | Internal and external donor compounds for olefin polymerization catalysts II | BASF CORPORATION (US) | 2013-10-29 | — | — | US | claimed |
| EP-2539375-A2 | INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS II | BASF Corporation (US) | 2013-01-02 | — | — | EP | claimed |
| WO-2011106480-A2 | INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS II | BASF CORPORATION (US) | 2011-09-01 | — | — | WO | claimed |
| US-20110207901-A1 | INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS II | BASF CATALYSTS LLC (US) | 2011-08-25 | — | — | US | claimed |
| EP-1601642-A4 | BIOAVAILABLE DIACYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX | RHEOGENE INC (US) | 2007-04-11 | — | — | EP | claimed |
| EP-1601642-A2 | BIOAVAILABLE DIACYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX | RheoGene, Inc. (US) | 2005-12-07 | — | — | EP | claimed |
| EP-0884096-B1 | Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use | KOCH MEMBRANE SYSTEMS INC (US) | 2005-09-14 | — | — | EP | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| WO-2004078924-A2 | BIOAVAILABLE DIACYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX | RHEOGENE, INC. (US) | 2004-09-16 | — | — | WO | claimed |
| US-20260144881-A1 | HPK1 TARGETING COMPOUNDS AND USES THEREOF | ARVINAS OPERATIONS, INC. (US) | 2026-05-28 | — | — | US | disclosed |
| US-4038396-A | ANTIPYRETICS, ANALGESICS | MERCK & CO., INC. (US) | 1977-07-26 | — | — | US | disclosed |
| US-4034007-A | Process for the production of halogenated aromatic carboxylic acids | TENNECO CHEMICALS, INC. (US) | 1977-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260144881-A1 | HPK1 TARGETING COMPOUNDS AND USES THEREOF | SGK1, PBK, SGK3 | HPGD 2936/4885MEN1 4196/4885MAPT 3413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.