Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ODC1 | P11926 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954611 | 1.00 | ODC1 (0.47) | ODC1LMNABLMSMN1; SMN2KDM4E | |
| SCHEMBL9953431 | 0.94 | ODC1 (0.41) | ODC1LMNABLMSMN1; SMN2KDM4E | |
| SCHEMBL9953696 | 0.94 | ODC1 (0.41) | ODC1LMNABLMSMN1; SMN2KDM4E | |
| SCHEMBL29116696 | 0.89 | ODC1 (0.56) | ODC1LMNABLMSMN1; SMN2KDM4E | |
| SCHEMBL2115160 | 0.82 | ODC1 (0.48) | ODC1LMNABLMSMN1; SMN2KDM4E | |
| SCHEMBL28869340 | 0.80 | ODC1 (0.47) | ODC1LMNABLMSMN1; SMN2KDM4E | |
| SCHEMBL3744397 | 0.77 | ODC1 (0.48) | ODC1LMNABLMSMN1; SMN2KDM4E | |
| SCHEMBL3744393 | 0.77 | ODC1 (0.48) | ODC1LMNABLMSMN1; SMN2KDM4E | |
| SCHEMBL3627363 | 0.77 | ODC1 (0.48) | ODC1LMNABLMSMN1; SMN2KDM4E | |
| SCHEMBL11849715 | 0.74 | ODC1 (0.43) | ODC1LMNABLMSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085586-A1 | MEXILETINE PRODRUGS | SHIRE, LLC (US) | 2012-06-28 | — | — | WO | disclosed |