Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ODC1 | P11926 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953431 | 1.00 | ODC1 (0.41) | ODC1LMNABLMSMN1; SMN2KDM4E | |
| SCHEMBL9954611 | 0.94 | ODC1 (0.47) | ODC1LMNABLMSMN1; SMN2KDM4E | |
| SCHEMBL9953669 | 0.94 | ODC1 (0.47) | ODC1LMNABLMSMN1; SMN2KDM4E | |
| SCHEMBL2115160 | 0.89 | ODC1 (0.48) | ODC1LMNABLMSMN1; SMN2KDM4E | |
| SCHEMBL28869340 | 0.87 | ODC1 (0.47) | ODC1LMNABLMSMN1; SMN2KDM4E | |
| SCHEMBL29116696 | 0.83 | ODC1 (0.56) | ODC1LMNABLMSMN1; SMN2KDM4E | |
| SCHEMBL31295695 | 0.79 | ODC1 (0.38) | ODC1LMNABLMSMN1; SMN2KDM4E | |
| SCHEMBL522662 | 0.78 | ODC1 (0.42) | ODC1LMNABLMSMN1; SMN2KDM4E | |
| SCHEMBL522663 | 0.78 | ODC1 (0.42) | ODC1LMNABLMSMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL8205379 | 0.76 | BLM (0.43) | ODC1LMNABLMSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085586-A1 | MEXILETINE PRODRUGS | SHIRE, LLC (US) | 2012-06-28 | — | — | WO | disclosed |