Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 18/20 | 0.84 |
| ▸ | PIK3CG | P48736 | 15/20 | 0.84 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.65 |
| ▸ | MTOR | P42345 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952648 | 0.95 | PI4KA (0.87) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL9953614 | 0.94 | PI4KA (0.79) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL9953828 | 0.93 | PI4KA (0.85) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL10289330 | 0.93 | PI4KA (0.82) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL9954916 | 0.93 | PI4KA (0.82) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL9952779 | 0.93 | PI4KA (0.82) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL9954471 | 0.92 | PI4KA (1.00) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL9953381 | 0.91 | PI4KA (0.85) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL9954489 | 0.91 | PI4KA (0.85) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL14247273 | 0.90 | PI4KA (0.71) | PI4KAPIK3CGPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |