Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.42 |
| ▸ | HCAR1 | Q9BXC0 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9955263 | 0.86 | KMT2A (0.60) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL9953653 | 0.83 | CA12 (0.51) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL9952831 | 0.82 | KDM4E (0.58) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL9954771 | 0.79 | KDM4E (0.54) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL9954834 | 0.79 | CA12 (0.57) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL9952534 | 0.78 | CA12 (0.56) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL9952357 | 0.77 | CA12 (0.57) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL9954144 | 0.76 | ALDH1A1 (0.71) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL10289354 | 0.75 | CA12 (0.53) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL10288885 | 0.74 | CA12 (0.51) | CA12CA1CA2CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |