Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 3/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | HRH2 | P25021 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28724179 | 0.83 | SCN1A (0.35) | SCN1ASCN2ASCN3ACHRM2ADRA2A | |
| SCHEMBL2449398 | 0.78 | TSHR (0.37) | SCN1ASCN2ASCN3ACHRM2ADRA2A | |
| SCHEMBL4122749 | 0.75 | SCN1A (0.41) | SCN1ASCN2ASCN3ACHRM2ADRA2A | |
| SCHEMBL1315134 | 0.71 | SCN1A (0.38) | SCN1ASCN2ASCN3ACHRM2ADRA2A | |
| SCHEMBL11009271 | 0.71 | SCN1A (0.36) | SCN1ASCN2ASCN3ACHRM2ADRA2A | |
| SCHEMBL8743019 | 0.70 | SCN1A (0.41) | SCN1ASCN2ASCN3ACHRM2ADRA2A | |
| SCHEMBL10438591 | 0.70 | IDO1 (0.39) | SCN1ASCN2ASCN3ACHRM2ADRA2A | |
| SCHEMBL3889071 | 0.70 | IDO1 (0.43) | HTR2AIDO1TDO2IDO2 | |
| SCHEMBL10438594 | 0.70 | IDO1 (0.42) | SCN1ASCN2ASCN3ACHRM2ADRA2A | |
| SCHEMBL705044 | 0.70 | IDO1 (0.39) | SCN1ASCN2ASCN3ACHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013192404-A1 | POLYHETEROSILOXANE COMPOSITION | DOW CORNING CORPORATION (US) | 2013-12-27 | — | — | WO | disclosed |
| US-20130284978-A1 | Polyheterosiloxane Composition Including Lanthanide Metal | DOW CORNING CORPORATION (US) | 2013-10-31 | — | — | US | disclosed |
| EP-2655482-A1 | POLYHETEROSILOXANE COMPOSITION INCLUDING LANTHANIDE METAL | Dow Corning Corporation (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012088439-A1 | POLYHETEROSILOXANE COMPOSITION INCLUDING LANTHANIDE METAL | DOW CORNING CORPORATION (US) | 2012-06-28 | — | — | WO | disclosed |