Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL670866 | 0.82 | NAPRT (0.57) | NAPRTNFE2L2KEAP1ALDH1A1KMT2A | |
| SCHEMBL30498935 | 0.82 | NAPRT (0.57) | NAPRTNFE2L2KEAP1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL28556626 | 0.80 | NAPRT (0.55) | NAPRTNFE2L2KEAP1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL19211717 | 0.80 | NAPRT (0.55) | NAPRTNFE2L2KEAP1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL29136849 | 0.80 | NAPRT (0.55) | NAPRTNFE2L2KEAP1ALDH1A1KMT2A | |
| SCHEMBL9954268 | 0.78 | KEAP1 (0.48) | NAPRTNFE2L2KEAP1CYP11B1CYP11B2 | |
| SCHEMBL3566251 | 0.77 | APOBEC3G (0.50) | ALDH1A1KMT2AL3MBTL1LMNA | |
| SCHEMBL29268395 | 0.77 | NAPRT (0.52) | NAPRTNFE2L2KEAP1CYP11B1CYP11B2 | |
| SCHEMBL12077955 | 0.76 | NAPRT (0.50) | NAPRTNFE2L2KEAP1ALDH1A1MAPT | |
| SCHEMBL27973675 | 0.75 | NAPRT (0.53) | NAPRTNFE2L2KEAP1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |