Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 19/20 | 0.61 |
| ▸ | PIK3CG | P48736 | 16/20 | 0.55 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14247707 | 0.89 | PI4KA (0.47) | PI4KAPIK3CGALOX5APFEN1 | |
| SCHEMBL9954290 | 0.89 | PI4KA (0.71) | PI4KAPIK3CG | |
| SCHEMBL9954511 | 0.87 | PI4KA (0.64) | PI4KAPIK3CG | |
| SCHEMBL9960507 | 0.87 | PI4KA (0.54) | PI4KAPIK3CG | |
| SCHEMBL9954271 | 0.86 | PI4KA (0.68) | PI4KAPIK3CG | |
| SCHEMBL9954408 | 0.86 | PI4KA (0.69) | PI4KAPIK3CG | |
| SCHEMBL9954715 | 0.86 | PI4KA (0.69) | PI4KAPIK3CG | |
| SCHEMBL9952892 | 0.85 | PI4KA (0.68) | PI4KAPIK3CG | |
| SCHEMBL9953643 | 0.84 | PI4KA (0.55) | PI4KAPIK3CG | |
| SCHEMBL9954587 | 0.84 | PI4KA (0.61) | PI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |