Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 16/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 13/20 | 0.55 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.43 |
| ▸ | DCK | P27707 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954675 | 0.84 | PI4KA (0.61) | PI4KAPIK3CG | |
| SCHEMBL9954428 | 0.84 | PI4KA (0.56) | PI4KAPIK3CG | |
| SCHEMBL9953943 | 0.83 | PI4KA (0.59) | PI4KAPIK3CG | |
| SCHEMBL9954217 | 0.81 | PI4KA (0.56) | PI4KAPIK3CGPIK3C3 | |
| SCHEMBL10288740 | 0.81 | PI4KA (0.53) | PI4KAPIK3CG | |
| SCHEMBL9954290 | 0.81 | PI4KA (0.71) | PI4KAPIK3CG | |
| SCHEMBL9954365 | 0.80 | PI4KA (0.70) | PI4KAPIK3CG | |
| SCHEMBL9954715 | 0.78 | PI4KA (0.69) | PI4KAPIK3CG | |
| SCHEMBL9954408 | 0.78 | PI4KA (0.69) | PI4KAPIK3CG | |
| SCHEMBL10289377 | 0.78 | PI4KA (0.49) | PI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |