Phosphoric Acid

Phosphoric Acid

SCHEMBL995486

O=P(O)(O)O.O=P([O-])([O-])O.O=P([O-])([O-])O.[H+].[H+].[Na+].[Na+]

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC34A1 Q06495 1/20 0.54
KDM4E B2RXH2 2/20 0.44
CYP2C19 P33261 1/20 0.44
KMT2A Q03164 1/20 0.44
LMNA P02545 2/20 0.44
CA2 P00918 1/20 0.36
CA1 P00915 2/20 0.35
CA4 P22748 2/20 0.35
CA5A P35218 2/20 0.35
CA5B Q9Y2D0 2/20 0.35
MMP2 P08253 1/20 0.31
THRB P10828 1/20 0.31
MAPK1 P28482 1/20 0.31
HSD17B10 Q99714 1/20 0.31
FDPS P14324 1/20 0.31
BLM P54132 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL18894574 1.00 SLC34A1 (0.54) SLC34A1KDM4ECYP2C19KMT2ALMNA
Phosphoric Acid SCHEMBL8011743 0.96 SLC34A1 (0.50) SLC34A1KDM4ECYP2C19KMT2ALMNA
Phosphoric Acid SCHEMBL27857924 0.95 SLC34A1 (0.58) SLC34A1KDM4ECYP2C19KMT2ALMNA
Phosphoric Acid SCHEMBL78045 0.95 SLC34A1 (0.58) SLC34A1KDM4ECYP2C19KMT2ALMNA
Phosphoric Acid SCHEMBL28948531 0.95 SLC34A1 (0.58) SLC34A1KDM4ECYP2C19KMT2ALMNA
Phosphoric Acid SCHEMBL7215415 0.95 SLC34A1 (0.58) SLC34A1KDM4ECYP2C19KMT2ALMNA
Phosphoric Acid SCHEMBL8068410 0.95 SLC34A1 (0.58) SLC34A1KDM4ECYP2C19KMT2ALMNA
Phosphoric Acid SCHEMBL1698246 0.95 SLC34A1 (0.58) SLC34A1KDM4ECYP2C19KMT2ALMNA
Phosphoric Acid SCHEMBL2779192 0.95 SLC34A1 (0.58) SLC34A1KDM4ECYP2C19KMT2ALMNA
Phosphoric Acid SCHEMBL39096 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2902068-B2 Apparatus for aspirating, irrigating and cleansing wounds SMITH & NEPHEW (GB) 2022-09-07 EP disclosed
EP-2902068-B1 Apparatus for aspirating, irrigating and cleansing wounds SMITH & NEPHEW (GB) 2019-08-07 EP disclosed
EP-2978890-B1 NOVEL METHOD FOR COLORATION AND TREATMENT OF SUBSTRATES UNIV LEEDS INNOVATIONS LTD (GB) 2019-06-19 EP disclosed
WO-2019020777-A1 LIQUID FORMULATION OF A VEGF ANTAGONIST FORMYCON AG (DE) 2019-01-31 WO disclosed
EP-3056241-B1 APPARATUS FOR ASPIRATING AND IRRIGATING THE WOUNDS SMITH & NEPHEW (GB) 2018-12-05 EP disclosed
EP-2305341-B1 Dressing for aspirating, irrigating and cleansing wounds SMITH & NEPHEW (GB) 2018-01-03 EP disclosed
EP-3210607-A1 SOLID PHARMACEUTICAL COMPOSITION Kyorin Pharmaceutical Co., Ltd. (JP) 2017-08-30 EP disclosed
EP-3202431-A1 WOUND TREATMENT APPARATUS Smith & Nephew PLC (GB) 2017-08-09 EP disclosed
EP-3167916-A1 WOUND TREATING APPARATUS AND METHOD Smith & Nephew PLC (GB) 2017-05-17 EP disclosed
EP-1874375-B1 WOUND TREATING APPARATUS AND METHOD SMITH & NEPHEW (GB) 2017-02-15 EP disclosed
WO-2005105180-A1 APPARATUS FOR ASPIRATING, IRRIGATING AND/OR CLEANSING OF WOUNDS SMITH & NEPHEW, PLC (GB) 2005-11-10 WO disclosed
WO-2005105179-A1 APPARATUS FOR CLEANSING WOUNDS WITH MEANS FOR SUPPLY OF THERMAL ENERGY TO THE THERAPY FLUID SMITH & NEPHEW, PLC (GB) 2005-11-10 WO disclosed
WO-2005105174-A1 WOUND CLEANSING APPARATUS WITH STRESS SMITH & NEPHEW, PLC (GB) 2005-11-10 WO disclosed
WO-2005105176-A1 WOUND CLEANSING APPARATUS WITH FLOWSTRESS SMITH & NEPHEW, PLC (GB) 2005-11-10 WO disclosed
WO-2005102415-A1 DRESSING AND APPARATUS FOR CLEANSING THE WOUNDS SMITH & NEPHEW, PLC (GB) 2005-11-03 WO disclosed
EP-1562668-A1 APPARATUS FOR ASPIRATING, IRRIGATING AND CLEANSING WOUNDS Smith & Nephew PLC (GB) 2005-08-17 EP disclosed
WO-2005046761-A1 WOUND CLEANSING APPARATUS WITH ACTIVES SMITH & NEPHEW PLC (GB) 2005-05-26 WO disclosed
WO-2005046760-A1 WOUND CLEANSING APPARATUS WITH HEAT SMITH & NEPHEW PLC (GB) 2005-05-26 WO disclosed
WO-2005046762-A1 WOUND CLEANSING APPARATUS WITH SCAFFOLD SMITH & NEPHEW PLC (GB) 2005-05-26 WO disclosed
WO-2004037334-A1 APPARATUS FOR ASPIRATING, IRRIGATING AND CLEANSING WOUNDS SMITH & NEPHEW PLC (GB) 2004-05-06 WO disclosed