Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CISD2 | Q8N5K1 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952844 | 0.85 | POLB (0.38) | CNR1CNR2ABHD6HPGDCA12 | |
| SCHEMBL31289787 | 0.83 | CA12 (0.39) | TSHRHTTCYP3A4HPGDCA12 | |
| SCHEMBL21827544 | 0.83 | TSHR (0.38) | CNR1CNR2ABHD6TSHRHTT | |
| SCHEMBL24683791 | 0.80 | TSHR (0.37) | CNR1CNR2ABHD6TSHRHTT | |
| SCHEMBL2526377 | 0.80 | ALDH1A1 (0.38) | TSHRHTTCYP3A4HPGDCISD2 | |
| SCHEMBL21634860 | 0.80 | CNR1 (0.34) | CNR1CNR2ABHD6 | |
| SCHEMBL23803699 | 0.79 | ALDH1A1 (0.37) | CNR1CNR2ABHD6TSHRHTT | |
| SCHEMBL24683784 | 0.76 | SCN9A (0.43) | CNR1CNR2ABHD6 | |
| SCHEMBL24683009 | 0.76 | CNR1 (0.37) | CNR1CNR2ABHD6TSHRHTT | |
| SCHEMBL30678416 | 0.76 | CNR1 (0.37) | CNR1CNR2ABHD6TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |