SCHEMBL9954989

SCHEMBL9954989

Brc1ccc(-c2ccccc2I)c(I)c1Br

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 1/20 0.32
PTPRC P08575 1/20 0.31
P2RX7 Q99572 1/20 0.31
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28228668 0.78 ALDH1A1 (0.39) ALDH1A1MAPK1
SCHEMBL28358787 0.77 ALDH1A1 (0.48) ALDH1A1MAPK1
SCHEMBL351923 0.75 ALDH1A1 (0.50) ALDH1A1MAPK1
SCHEMBL1226577 0.74 MEN1 (0.39) ALDH1A1MAPK1PTPRCP2RX7CYP1A2
SCHEMBL31365965 0.73 ALDH1A1 (0.48) ALDH1A1MAPK1PTPRC
SCHEMBL18830631 0.73 ALDH1A1 (0.37) ALDH1A1MAPK1PTPRC
SCHEMBL11709707 0.72 ALDH1A1 (0.33) ALDH1A1MAPK1CYP1A2
SCHEMBL14236912 0.71 MEN1 (0.42) ALDH1A1MAPK1PTPRCP2RX7CYP1A2
SCHEMBL1768311 0.70 ALDH1A1 (0.44) ALDH1A1MAPK1
SCHEMBL30106746 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114349790-A Preparation method of phosphine oxide type TADF (TADF-based organic photoelectric material) 安阳工学院 2022-04-15 CN claimed
CN-109970791-B Indenotriphenylene derivative and organic electroluminescent device using the same 机光科技股份有限公司 2022-07-22 CN disclosed
CN-114349790-A Preparation method of phosphine oxide type TADF (TADF-based organic photoelectric material) 安阳工学院 2022-04-15 CN disclosed
WO-2012087243-A1 NEW P-TYPE LOW BANDGAP POLYMERS AND THEIR USE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-06-28 WO disclosed