Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27895093 | 0.87 | KMT2A (0.42) | MEN1KMT2ANPC1ALDH1A1SHMT2 | |
| SCHEMBL27895096 | 0.86 | MEN1 (0.47) | KDM4EMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL27895094 | 0.82 | MEN1 (0.48) | MEN1KMT2ANPC1ALDH1A1MCOLN3 | |
| SCHEMBL9958946 | 0.81 | KMT2A (0.47) | KDM4EMEN1KMT2AALDH1A1MCOLN3 | |
| SCHEMBL732352 | 0.81 | NPC1 (0.52) | KDM4EMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL27895098 | 0.79 | MEN1 (0.46) | KDM4EMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL11139152 | 0.77 | KDM4E (0.48) | KDM4EMEN1KMT2AALDH1A1MCOLN3 | |
| SCHEMBL855488 | 0.75 | HSD17B10 (0.48) | KDM4EMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL14247593 | 0.75 | PDGFRB (0.49) | KDM4EKMT2AALDH1A1MCOLN3PKM | |
| SCHEMBL9953525 | 0.75 | TSHR (0.50) | KDM4EMEN1KMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |