SCHEMBL9955927

SCHEMBL9955927

CCc1ccc(CC(C)(C)C=CCc2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.47
MAOB P27338 1/20 0.45
SLC6A2 P23975 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
LMNA P02545 1/20 0.38
CYP2D6 P10635 1/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
ARG2 P78540 1/20 0.37
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
KIF11 P52732 2/20 0.34
RAB9A P51151 2/20 0.34
TRPA1 O75762 1/20 0.34
KDM4E B2RXH2 1/20 0.34
NPC1 O15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9955924 1.00 TP53 (0.47) TP53MAOBSLC6A2TAAR1LMNA
SCHEMBL6841872 0.74 MAOB (0.61) TP53MAOBSLC6A2TAAR1LMNA
SCHEMBL6546523 0.72 TP53 (0.54) TP53MAOBLMNACA1CA2
Ethylbenzene SCHEMBL27405402 0.71 TP53 (0.93) TP53TAAR1ALDH1A1MEN1KMT2A
Allylbenzene SCHEMBL11226285 0.70 TP53 (0.64) TP53MAOBCA1CA2ARG2
SCHEMBL1072575 0.70 SLC6A2 (0.52) TP53MAOBSLC6A2TAAR1LMNA
SCHEMBL6546781 0.69 TP53 (0.50) TP53MAOBALDH1A1CYP3A4MEN1
SCHEMBL111724 0.69 ALDH1A1 (0.47) TP53TAAR1LMNACYP2D6CA2
Ethylbenzene SCHEMBL1330604 0.68
Ethylbenzene SCHEMBL11223212 0.68 TP53 (1.00) TP53TAAR1ALDH1A1CYP3A4RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2655307-B1 COMPOUNDS CAPABLE OF RELEASING FRAGRANT COMPOUNDS GIVAUDAN SA (CH) 2018-08-01 EP claimed
US-9193935-B2 Compounds capable of releasing fragrant compounds GIVAUDAN S.A. (CH) 2015-11-24 US claimed
US-20130316938-A1 Compounds Capable Of Releasing Fragrant Compounds GIVAUDAN S.A. (CH) 2013-11-28 US claimed
EP-2655307-A1 COMPOUNDS CAPABLE OF RELEASING FRAGRANT COMPOUNDS Givaudan SA (CH) 2013-10-30 EP claimed
WO-2012085287-A1 COMPOUNDS CAPABLE OF RELEASING FRAGRANT COMPOUNDS GIVAUDAN SA (CH) 2012-06-28 WO claimed
EP-2655307-B1 COMPOUNDS CAPABLE OF RELEASING FRAGRANT COMPOUNDS GIVAUDAN SA (CH) 2018-08-01 EP disclosed
US-9193935-B2 Compounds capable of releasing fragrant compounds GIVAUDAN S.A. (CH) 2015-11-24 US disclosed
US-20130316938-A1 Compounds Capable Of Releasing Fragrant Compounds GIVAUDAN S.A. (CH) 2013-11-28 US disclosed