Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | AOC2 | O75106 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6323330 | 0.78 | ALDH1A1 (0.44) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL11519676 | 0.77 | MEN1 (0.38) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL7524425 | 0.74 | ALDH1A1 (0.42) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL7522348 | 0.72 | ALDH1A1 (0.41) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL816701 | 0.72 | CYP2D6 (0.55) | ALDH1A1POLBKDM4EKMT2ALMNA | |
| SCHEMBL7936994 | 0.72 | HSD17B10 (0.42) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL9375286 | 0.70 | — | — | |
| SCHEMBL11232760 | 0.70 | — | — | |
| SCHEMBL11573242 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL11576722 | 0.70 | CYP2D6 (0.52) | ALDH1A1POLBKDM4EKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085501-A1 | 8 - SULFO - IMIDAZOTETRAZIN- 4 - ONE COMPOUNDS AND THEIR USE AS ANTICANCER DRUG | PHARMINOX LIMITED (GB) | 2012-06-28 | — | — | WO | disclosed |