SCHEMBL9957883

SCHEMBL9957883

CCc1ccc(-c2c3ccccc3c(-c3ccc4c(c3)C(C)(C)c3cc(OB(O)O)ccc3-4)c3ccccc23)cc1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 6/20 0.33
ALK Q9UM73 8/20 0.32
EGFR P00533 1/20 0.32
MET P08581 1/20 0.32
CTSV O60911 1/20 0.30
CTSL P07711 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9957684 0.89 DHODH (0.37) PDK2ALKCTSVCTSL
SCHEMBL9957858 0.89 PDK2 (0.35) PDK2ALK
SCHEMBL9957601 0.87 PDK2 (0.42) PDK2
SCHEMBL9961016 0.79 PDK2 (0.34) PDK2EGFRMETCTSVCTSL
SCHEMBL5467173 0.78 PDK2 (0.45) PDK2
SCHEMBL10153431 0.77 PDK2 (0.42) PDK2ALK
SCHEMBL10153583 0.76 PDK2 (0.41) PDK2
SCHEMBL10153380 0.76 PDK2 (0.41) PDK2ALK
SCHEMBL10153359 0.76 PDK2 (0.45) PDK2
SCHEMBL10153463 0.75 PDK2 (0.44) PDK2ALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1221434-B1 HYDROCARBON COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUI CHEMICALS INC (JP) 2012-06-27 EP disclosed