SCHEMBL9957684

SCHEMBL9957684

CCCCc1ccc(-c2c3ccccc3c(-c3ccc4c(c3)C(C)(C)c3cc(OB(O)O)ccc3-4)c3ccccc23)cc1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.37
MPL P40238 3/20 0.35
PDK2 Q15119 3/20 0.34
CTSV O60911 1/20 0.34
CTSL P07711 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
ALK Q9UM73 1/20 0.33
PTPN1 P18031 4/20 0.32
BRS3 P32247 1/20 0.32
PTPN11 Q06124 1/20 0.32
HSD11B1 P28845 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9957883 0.89 PDK2 (0.33) PDK2CTSVCTSLALK
SCHEMBL9957858 0.85 PDK2 (0.35) PDK2ALKPTPN1
SCHEMBL9957601 0.84 PDK2 (0.42) PDK2CA1CA2
SCHEMBL14600391 0.78 PDK2 (0.47) DHODHPDK2ALKPTPN1PTPN11
SCHEMBL14600345 0.78 CYP2D6 (0.45) PDK2CTSVCTSLALK
SCHEMBL14600446 0.77 PDK2 (0.46) DHODHPDK2ALKPTPN1PTPN11
SCHEMBL14600410 0.77 CYP2D6 (0.44) PDK2CTSVCTSLALK
SCHEMBL14600421 0.77 CYP2D6 (0.44) PDK2CTSVCTSLALK
SCHEMBL14600359 0.76 PDK2 (0.46) DHODHPDK2ALKPTPN1PTPN11
SCHEMBL14600489 0.76 CYP2D6 (0.43) PDK2CTSVCTSLALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1221434-B1 HYDROCARBON COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUI CHEMICALS INC (JP) 2012-06-27 EP disclosed