SCHEMBL9958069

SCHEMBL9958069

Brc1c2ccccc2c(-c2c3ccccc3c(-c3ccc(-c4ccccc4)cc3)c3ccccc23)c2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.48
ALDH1A1 P00352 3/20 0.48
MAPT P10636 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
KDM4E B2RXH2 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
ACHE P22303 2/20 0.42
ESR1 P03372 5/20 0.38
ESR2 Q92731 5/20 0.38
CYP1A2 P05177 2/20 0.37
HTT P42858 2/20 0.37
CYP3A4 P08684 2/20 0.37
LMNA P02545 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MMP3 P08254 1/20 0.37
BCL2L1 Q07817 1/20 0.37
HPGD P15428 1/20 0.37
CYP2C19 P33261 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29603166 0.98 MAPK1 (0.50) MAPK1ALDH1A1MAPTTDP1KDM4E
SCHEMBL1534946 0.98 MAPK1 (0.50) MAPK1ALDH1A1MAPTTDP1KDM4E
SCHEMBL12560730 0.98 MAPK1 (0.50) MAPK1ALDH1A1MAPTTDP1KDM4E
Biphenyl SCHEMBL27626716 0.95 MAPK1 (0.48) MAPK1ALDH1A1MAPTTDP1KDM4E
SCHEMBL2185513 0.95 MAPK1 (0.48) MAPK1ALDH1A1MAPTTDP1KDM4E
SCHEMBL12560663 0.95 MAPK1 (0.48) MAPK1ALDH1A1MAPTTDP1KDM4E
SCHEMBL295397 0.93 MAPK1 (0.50) MAPK1ALDH1A1MAPTTDP1KDM4E
SCHEMBL30396122 0.93 MAPK1 (0.50) MAPK1ALDH1A1MAPTTDP1KDM4E
SCHEMBL19862724 0.91 MAPK1 (0.44) MAPK1ALDH1A1MAPTTDP1KDM4E
SCHEMBL3000291 0.91 KDM4E (0.42) MAPK1ALDH1A1MAPTTDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1221434-B1 HYDROCARBON COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUI CHEMICALS INC (JP) 2012-06-27 EP disclosed