SCHEMBL19862724

SCHEMBL19862724

Brc1c2ccccc2c(-c2ccc(-c3cc(-c4ccccc4)cc(-c4ccccc4)c3)cc2)c2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.44
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
MAPT P10636 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
ACHE P22303 2/20 0.39
ESR1 P03372 4/20 0.39
ESR2 Q92731 4/20 0.39
PTPN1 P18031 1/20 0.36
EGFR P00533 1/20 0.36
GRIN2D O15399 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2B Q13224 1/20 0.36
GRIN2C Q14957 1/20 0.36
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35
HTT P42858 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2085368 0.94 CRHBP (0.43) MAPK1ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL29603166 0.94 MAPK1 (0.50) MAPK1ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL12560730 0.94 MAPK1 (0.50) MAPK1ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL1534946 0.94 MAPK1 (0.50) MAPK1ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL9958069 0.91 MAPK1 (0.48) MAPK1ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL12560663 0.91 MAPK1 (0.48) MAPK1ALDH1A1KDM4EL3MBTL1MAPT
Biphenyl SCHEMBL27626716 0.91 MAPK1 (0.48) MAPK1ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL2082935 0.90 MAPK1 (0.43) MAPK1ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL15480736 0.90 CRHBP (0.41) MAPK1ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL12560721 0.89 MAPT (0.44) MAPK1ALDH1A1KDM4EL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180171218-A1 ORGANIC ELECTROLUMINESCENT DEVICE GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD . (CN) 2018-06-21 US disclosed
US-20180047909-A1 ORGANIC ELECTRONIC MATERIAL GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD . (CN) 2018-02-15 US disclosed
US-20180047910-A1 ORGANIC ELECTROLUMINESCENT DEVICE GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD . (CN) 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180047909-A1 ORGANIC ELECTRONIC MATERIAL OCIAD1, OCIAD2, EED MAPK1 2362/4885ALDH1A1 278/4885KDM4E 2521/4885
US-20180047910-A1 ORGANIC ELECTROLUMINESCENT DEVICE OCIAD1, OCIAD2, CTNND1 MAPK1 702/4885ALDH1A1 669/4885KDM4E 2575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.