Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 18/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3604768 | 0.82 | GCK (1.00) | GCK | |
| SCHEMBL10230946 | 0.76 | GCK (0.64) | GCKMEN1USP2LMNAMAPT | |
| SCHEMBL27669120 | 0.75 | PTGS2 (0.52) | GCKMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL2668165 | 0.74 | GCK (0.56) | GCKMAPTHTT | |
| SCHEMBL2666831 | 0.73 | GCK (0.64) | GCKMEN1USP2LMNAMAPT | |
| SCHEMBL2646026 | 0.73 | GCK (0.81) | GCKMEN1USP2LMNAMAPT | |
| SCHEMBL2646029 | 0.73 | GCK (0.81) | GCKMEN1USP2LMNAMAPT | |
| SCHEMBL2646202 | 0.73 | GCK (0.81) | GCKMEN1USP2LMNAMAPT | |
| SCHEMBL2646391 | 0.73 | GCK (0.81) | GCKMEN1USP2LMNAMAPT | |
| SCHEMBL2646199 | 0.73 | GCK (0.81) | GCKMEN1USP2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125735-B1 | 2,2,2-TRI-SUBSTITUTED ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS PRIVATE LTD (IN) | 2012-06-27 | — | — | EP | claimed |