Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 2/20 | 0.66 |
| ▸ | TUBB | P07437 | 2/20 | 0.66 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.66 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.66 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.66 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.66 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.66 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.66 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.66 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.66 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.66 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.66 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.66 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.66 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.66 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9958972 | 0.93 | ABCG2 (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10307571 | 0.87 | EPHX2 (0.76) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL15452189 | 0.87 | EPHX2 (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL15449134 | 0.86 | ABCB1 (0.65) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10307572 | 0.84 | ABCB1 (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29750809 | 0.82 | TUBB4A (0.86) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1252875 | 0.82 | TUBB4A (0.86) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL15676566 | 0.80 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| 3,3'-O-Dimethylquercetin SCHEMBL29443769 | 0.80 | ABCG2 (0.84) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| 3,3'-O-Dimethylquercetin SCHEMBL1252850 | 0.80 | ABCG2 (0.84) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468741-A1 | Novel quercetin derivatives, their preparation, pharmaceutical compositions containing them and their use | Bel/Novamann International s.r.o. (SK) | 2012-06-27 | — | — | EP | disclosed |