Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | VDR | P11473 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1745483 | 0.79 | BCHE (0.51) | FFAR1MAPK1PPARDVDRPPARA | |
| SCHEMBL3921153 | 0.78 | FFAR1 (0.44) | FFAR1MAPK1PPARDVDRPPARA | |
| SCHEMBL1745485 | 0.78 | FFAR1 (0.53) | FFAR1MAPK1PPARDVDRPTPN1 | |
| SCHEMBL1747386 | 0.77 | TP53 (0.54) | FFAR1MAPK1PPARDVDRAPP | |
| SCHEMBL1745242 | 0.77 | MAPT (0.52) | FFAR1MAPK1PPARDVDRAPP | |
| SCHEMBL1745444 | 0.76 | KMT2A (0.48) | FFAR1PPARDVDR | |
| SCHEMBL1746563 | 0.76 | KMT2A (0.49) | FFAR1PPARDVDRPPARGAPP | |
| SCHEMBL1747402 | 0.75 | FFAR1 (0.48) | FFAR1PPARDVDRPTPN2PTPN1 | |
| SCHEMBL1745481 | 0.75 | NPSR1 (0.47) | FFAR1PPARDVDR | |
| SCHEMBL3920081 | 0.74 | FFAR1 (0.45) | FFAR1PPARDVDRPPARAFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1698624-B1 | PHENYLPROPANOIC ACID DERIVATIVES | TAKEDA PHARMACEUTICAL (JP) | 2012-06-27 | — | — | EP | disclosed |