Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11668319 | 0.91 | EPHX1 (0.46) | EPHX1TP53LMNAMAPTSMN1; SMN2 | |
| SCHEMBL29037027 | 0.81 | EPHX1 (0.50) | EPHX1TP53LMNAMAPTSMN1; SMN2 | |
| SCHEMBL11591769 | 0.81 | TP53 (0.48) | EPHX1TP53LMNAMAPTSMN1; SMN2 | |
| SCHEMBL9766174 | 0.81 | TP53 (0.48) | EPHX1TP53LMNAMAPTSMN1; SMN2 | |
| SCHEMBL28508056 | 0.79 | EPHX1 (0.48) | EPHX1TP53LMNAMAPTSMN1; SMN2 | |
| SCHEMBL9760861 | 0.79 | PREP (0.32) | — | |
| SCHEMBL11440912 | 0.78 | EPHX1 (0.43) | EPHX1CYP1A2TSHRSIGMAR1SHBG | |
| SCHEMBL17529700 | 0.78 | EPHX1 (0.43) | EPHX1TP53LMNAMAPTSMN1; SMN2 | |
| SCHEMBL2593250 | 0.78 | EPHX1 (0.43) | EPHX1CYP1A2TSHRSIGMAR1SHBG | |
| SCHEMBL11440474 | 0.78 | EPHX1 (0.43) | EPHX1CYP1A2TSHRSIGMAR1SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2087067-B1 | CYCLOHEXYLENE REACTIVE MESOGENS AND THEIR APPLICATIONS | MERCK PATENT GMBH (DE) | 2012-06-27 | — | — | EP | disclosed |