Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11591769 | 1.00 | TP53 (0.48) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL10358405 | 0.98 | TP53 (0.50) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL9122339 | 0.96 | TP53 (0.46) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL2035572 | 0.91 | TP53 (0.52) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL4298582 | 0.82 | TP53 (0.56) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL11607011 | 0.82 | TP53 (0.47) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL8413380 | 0.82 | TP53 (0.47) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL2858662 | 0.82 | TP53 (0.47) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL31562869 | 0.82 | TP53 (0.47) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL9958443 | 0.81 | EPHX1 (0.43) | TP53KDM4EGMNNLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991010679-A2 | RENIN INHIBITING PEPTIDES HAVING AN 'alpha'-HETEROATOM AMINO ACID AT THE P3 POSITION | WARNER LAMBERT CO (US) | 1991-07-25 | — | — | WO | disclosed |