Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 15/20 | 0.45 |
| ▸ | AXL | P30530 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 5/20 | 0.42 |
| ▸ | RAF1 | P04049 | 2/20 | 0.40 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4330528 | 1.00 | MET (0.45) | METAXLNTRK1KDRRAF1 | |
| SCHEMBL4344063 | 0.96 | MET (0.46) | METAXLNTRK1KDRRAF1 | |
| SCHEMBL4334640 | 0.92 | MET (0.48) | METAXLNTRK1KDRRAF1 | |
| SCHEMBL4328769 | 0.92 | MET (0.49) | METAXLNTRK1KDRRAF1 | |
| SCHEMBL4342724 | 0.91 | MET (0.47) | METKDRRAF1 | |
| SCHEMBL4335387 | 0.90 | MET (0.48) | METAXLNTRK1KDRRAF1 | |
| SCHEMBL4328688 | 0.90 | MET (0.48) | METAXLKDRBRAF | |
| SCHEMBL14391999 | 0.89 | MET (0.48) | METAXLNTRK1KDRRAF1 | |
| SCHEMBL4324329 | 0.89 | MET (0.48) | METAXLNTRK1KDRRAF1 | |
| SCHEMBL4329642 | 0.89 | MET (0.48) | METAXLNTRK1KDRRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1719762-B1 | NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (1) | EISAI R&D MAN CO LTD (JP) | 2012-06-27 | — | — | EP | claimed |