Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CENPE | Q02224 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14859905 | 0.90 | CENPE (0.59) | CENPE | |
| SCHEMBL3467520 | 0.86 | CENPE (0.66) | CENPEKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL3461347 | 0.84 | CENPE (0.73) | CENPEKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL2104989 | 0.84 | CENPE (0.73) | CENPEKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL3461739 | 0.83 | CENPE (0.67) | CENPEKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL2103611 | 0.82 | CENPE (0.84) | CENPEKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL2101424 | 0.82 | CENPE (0.84) | CENPEKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL2105380 | 0.82 | CENPE (0.73) | CENPEKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL2106126 | 0.82 | CENPE (0.84) | CENPEKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL3461906 | 0.82 | CENPE (0.74) | CENPEKDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207340-B2 | Imidazopyridinyl benzamide mitotic kinesin inhibitors | CYTOKINETICS, INCORPORATED (US) | 2012-06-26 | — | — | US | disclosed |