Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 3/20 | 0.52 |
| ▸ | CPA1 | P15085 | 2/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP7 | P09237 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15592756 | 0.87 | MME (0.58) | MMEL3MBTL1ACECPA1ACE2 | |
| SCHEMBL2781126 | 0.87 | MME (0.58) | MMEL3MBTL1ACECPA1ACE2 | |
| SCHEMBL123574 | 0.87 | MME (0.58) | MMEL3MBTL1ACECPA1ACE2 | |
| SCHEMBL7379335 | 0.87 | MME (0.70) | MMEL3MBTL1ACECPA1ACE2 | |
| SCHEMBL9068541 | 0.87 | MME (0.70) | MMEL3MBTL1ACECPA1ACE2 | |
| SCHEMBL8254204 | 0.86 | MME (0.56) | MMEL3MBTL1ACECPA1ACE2 | |
| Hydrochloric Acid SCHEMBL28854963 | 0.86 | MME (0.56) | MMEL3MBTL1ACECPA1ACE2 | |
| SCHEMBL22624332 | 0.86 | MME (0.56) | MMEL3MBTL1ACECPA1ACE2 | |
| SCHEMBL5870242 | 0.86 | MME (0.56) | MMEL3MBTL1ACECPA1ACE2 | |
| SCHEMBL23156997 | 0.84 | MME (0.55) | MMEL3MBTL1ACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120198576-A1 | METHODS FOR MAKING EMBRYONIC CELLS, EMBRYOS, AND ANIMALS SENSITIZED TO STRESS | BRANDEIS UNIVERSITY (US) | 2012-08-02 | — | — | US | disclosed |
| WO-2011002955-A2 | METHODS FOR MAKING EMBRYONIC CELLS, EMBRYOS, AND ANIMALS SENSITIZED TO STRESS | BRANDEIS UNIVERSITY (US) | 2011-01-06 | — | — | WO | disclosed |