Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9960249 | 0.79 | CRBN (0.32) | — | |
| SCHEMBL30234510 | 0.69 | NOS3 (0.31) | NOS3NOS1NOS2 | |
| SCHEMBL9959584 | 0.67 | CYP19A1 (0.36) | — | |
| SCHEMBL11822242 | 0.65 | — | — | |
| SCHEMBL2980718 | 0.64 | MAPT (0.33) | — | |
| SCHEMBL8468449 | 0.64 | — | — | |
| SCHEMBL18789034 | 0.64 | POLB (0.36) | — | |
| SCHEMBL15418578 | 0.62 | CYP19A1 (0.31) | — | |
| SCHEMBL28240899 | 0.62 | CRBN (0.32) | — | |
| SCHEMBL9509490 | 0.61 | NOS3 (0.33) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2467364-A2 | NITROGEN-CONTAINING COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF ATRIAL FIBRILLATION | Otsuka Pharmaceutical Co., Ltd. (JP) | 2012-06-27 | — | — | EP | disclosed |