SCHEMBL9959932

SCHEMBL9959932

COc1c(C(C)(C)C)cc2c(c1-c1ccccc1)CC(CC(C)C)=C2

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 5/20 0.37
PDE4A P27815 4/20 0.37
PDE4C Q08493 4/20 0.37
PDE4D Q08499 4/20 0.37
TNFRSF1A P19438 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9959044 0.86 PDE4B (0.35) PDE4BPDE4APDE4CPDE4DTNFRSF1A
SCHEMBL3742137 0.81 PDE4B (0.39) PDE4BPDE4APDE4CPDE4DTNFRSF1A
SCHEMBL19313378 0.80 HTR2C (0.31)
SCHEMBL30943315 0.77 TDO2 (0.31)
SCHEMBL22687558 0.77 TDO2 (0.31)
SCHEMBL14645948 0.75
SCHEMBL20165704 0.73 CNR2 (0.30)
SCHEMBL31355502 0.73 CNR2 (0.33)
SCHEMBL19313306 0.73
SCHEMBL29873997 0.73 CNR2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10364307-B2 Process for producing propylene copolymers in gas phase BOREALIS AG (AT) 2019-07-30 US disclosed
EP-2995629-B1 Process for producing propylene copolymers in gas phase BOREALIS AG (AT) 2018-03-07 EP disclosed
EP-2995629-B1 Process for producing propylene copolymers in gas phase BOREALIS AG (AT) 2018-03-07 EP disclosed
US-20170247484-A1 PROCESS FOR PRODUCING PROPYLENE COPOLYMERS IN GAS PHASE BOREALIS AG (AT) 2017-08-31 US disclosed
US-20170247484-A1 PROCESS FOR PRODUCING PROPYLENE COPOLYMERS IN GAS PHASE BOREALIS AG (AT) 2017-08-31 US disclosed
WO-2016038210-A1 PROCESS FOR PRODUCING PROPYLENE COPOLYMERS IN GAS PHASE BOREALIS AG (AT) 2016-03-17 WO disclosed
EP-2995629-A1 Process for producing propylene copolymers in gas phase Borealis AG (AT) 2016-03-16 EP disclosed
EP-2995629-A1 Process for producing propylene copolymers in gas phase Borealis AG (AT) 2016-03-16 EP disclosed
EP-2657285-B1 moulded polypropylene with high content of beta form BOREALIS AG (AT) 2015-07-22 EP disclosed
US-9079985-B2 Bridged metallocene catalysts BOREALIS AG (AT) 2015-07-14 US disclosed
US-9079985-B2 Bridged metallocene catalysts BOREALIS AG (AT) 2015-07-14 US disclosed
US-20140018506-A1 BRIDGED METALLOCENE CATALYSTS BOREALIS AG (AT) 2014-01-16 US disclosed
US-20140018506-A1 BRIDGED METALLOCENE CATALYSTS BOREALIS AG (AT) 2014-01-16 US disclosed
EP-2655431-A1 BRIDGED METALLOCENE CATALYSTS Borealis AG (AT) 2013-10-30 EP disclosed
EP-2657285-A1 Moulded polypropylene with high content of beta form Borealis AG (AT) 2013-10-30 EP disclosed
WO-2012084961-A1 BRIDGED METALLOCENE CATALYSTS BOREALIS AG (AT) 2012-06-28 WO disclosed
WO-2012084961-A1 BRIDGED METALLOCENE CATALYSTS BOREALIS AG (AT) 2012-06-28 WO disclosed