Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 7/20 | 0.46 |
| ▸ | CYP26A1 | O43174 | 10/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9959969 | 0.79 | HTT (0.50) | KCNA5CYP3A4CYP19A1 | |
| SCHEMBL1238297 | 0.74 | KCNA5 (0.47) | KCNA5BRPF1 | |
| SCHEMBL15986392 | 0.73 | KCNA5 (0.57) | KCNA5CYP3A4BRPF1 | |
| Hydrochloric Acid SCHEMBL15986397 | 0.73 | KCNA5 (0.47) | KCNA5BRPF1 | |
| SCHEMBL1239784 | 0.72 | KCNA5 (0.58) | KCNA5BRPF1 | |
| SCHEMBL1238562 | 0.72 | KCNA5 (0.55) | KCNA5BRPF1 | |
| SCHEMBL1239408 | 0.72 | KCNA5 (0.52) | KCNA5BRPF1 | |
| SCHEMBL1239839 | 0.71 | KCNA5 (0.58) | KCNA5BRPF1 | |
| SCHEMBL12080777 | 0.71 | KCNA5 (0.54) | KCNA5BRPF1 | |
| SCHEMBL1238540 | 0.70 | KCNA5 (0.44) | KCNA5BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2467364-A2 | NITROGEN-CONTAINING COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF ATRIAL FIBRILLATION | Otsuka Pharmaceutical Co., Ltd. (JP) | 2012-06-27 | — | — | EP | disclosed |