Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | LIG1 | P18858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5098437 | 0.84 | ALDH1A1 (0.55) | GAATSHRLIG1ALDH1A1KDM4E | |
| SCHEMBL18614861 | 0.84 | GAA (0.70) | GAATSHRLIG1ALDH1A1KDM4E | |
| SCHEMBL3316495 | 0.84 | GAA (0.70) | GAATSHRLIG1ALDH1A1KDM4E | |
| SCHEMBL8168167 | 0.83 | TSHR (0.68) | GAATSHRLIG1ALDH1A1KDM4E | |
| SCHEMBL20471955 | 0.83 | TSHR (0.68) | GAATSHRLIG1ALDH1A1KDM4E | |
| SCHEMBL3314718 | 0.83 | GAA (1.00) | GAATSHRLIG1ALDH1A1KDM4E | |
| SCHEMBL20471974 | 0.83 | GAA (0.68) | GAATSHRLIG1ALDH1A1KDM4E | |
| SCHEMBL3319882 | 0.83 | GAA (0.68) | GAATSHRLIG1ALDH1A1KDM4E | |
| SCHEMBL4296273 | 0.81 | GAA (0.67) | GAATSHRLIG1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL8164468 | 0.81 | TSHR (0.66) | GAATSHRLIG1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215050-B1 | MANUFACTURING METHOD OF 2-HYDROXY-5-PHENYLALKYLAMINOBENZOIC ACID DERIVATIVES AND THEIR SALTS | NEUROTECH PHARMACEUTICALS CO LTD (KR) | 2012-06-27 | — | — | EP | claimed |