Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 13/20 | 0.57 |
| ▸ | FNTB | P49356 | 13/20 | 0.57 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1198369 | 0.86 | FNTA (0.62) | FNTAFNTBPGGT1BIDO1 | |
| SCHEMBL168438 | 0.86 | FNTA (0.62) | FNTAFNTBPGGT1BIDO1 | |
| SCHEMBL7607330 | 0.77 | FNTA (0.38) | FNTAFNTBPGGT1B | |
| SCHEMBL13186537 | 0.73 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL5733786 | 0.73 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL3436599 | 0.71 | FNTA (0.81) | FNTAFNTB | |
| SCHEMBL5514757 | 0.69 | FNTA (0.80) | FNTAFNTBPGGT1BIDO1 | |
| SCHEMBL5225577 | 0.69 | FNTA (0.58) | FNTAFNTBPGGT1BIDO1 | |
| SCHEMBL5221738 | 0.69 | FNTA (0.58) | FNTAFNTBPGGT1BIDO1 | |
| SCHEMBL4382960 | 0.67 | FNTA (0.52) | FNTAFNTBPGGT1BIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2654748-A1 | INDAZOLE DERIVATIVES USEFUL AS ERK INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012087772-A1 | INDAZOLE DERIVATIVES USEFUL AS ERK INHIBITORS | SCHERING CORPORATION (US) | 2012-06-28 | — | — | WO | disclosed |