Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 7/20 | 0.35 |
| ▸ | RAB9A | P51151 | 7/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3468880 | 0.76 | OGA (0.44) | OGANPC1RAB9ATSHRNPSR1 | |
| SCHEMBL14403537 | 0.72 | NPC1 (0.51) | OGANPC1RAB9ATSHRNPSR1 | |
| SCHEMBL3469499 | 0.72 | RAB9A (0.55) | OGANPC1RAB9ATSHRNPSR1 | |
| SCHEMBL3468859 | 0.72 | USP2 (0.38) | OGANPC1RAB9AUSP2TSHR | |
| SCHEMBL3468716 | 0.71 | NPC1 (0.56) | OGANPC1RAB9ATSHRSMN1; SMN2 | |
| SCHEMBL3468608 | 0.70 | HRH3 (0.41) | OGANPC1RAB9AHTR6SMN1; SMN2 | |
| SCHEMBL9959266 | 0.70 | OGA (0.40) | OGANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL3468609 | 0.70 | HPGD (0.58) | NPC1RAB9ATSHRSMN1; SMN2MAPT | |
| SCHEMBL3468671 | 0.69 | RAB9A (0.49) | OGANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL3468828 | 0.69 | DPP4 (0.46) | OGANPC1RAB9ATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999120-B1 | BENZOTHIAZOLES HAVING HISTAMINE H3 RECEPTOR ACTIVITY | HIGH POINT PHARMACEUTICALS LLC (US) | 2012-06-27 | — | — | EP | disclosed |