Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.30 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9960910 | 0.79 | HTT (0.32) | MYCGRIA2GRIA4POLBHTT | |
| SCHEMBL9961034 | 0.71 | NOTUM (0.34) | MYCGRIA2GRIA4HTT | |
| SCHEMBL9960743 | 0.71 | KMT2A (0.34) | HTT | |
| SCHEMBL9960871 | 0.70 | DGAT1 (0.30) | — | |
| SCHEMBL9960849 | 0.70 | PLA2G1B (0.32) | — | |
| SCHEMBL9960959 | 0.70 | MAPK1 (0.32) | — | |
| SCHEMBL9960700 | 0.69 | NOTUM (0.34) | — | |
| SCHEMBL16144911 | 0.69 | TSHR (0.34) | GRIA2GRIA4 | |
| SCHEMBL9960992 | 0.69 | MYC (0.35) | MYCPOLBHTT | |
| SCHEMBL9961025 | 0.67 | GRIA2 (0.37) | MYCGRIA2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655323-A1 | INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES | LEO LABORATORIES LIMITED (IE) | 2013-10-30 | — | — | EP | claimed |
| WO-2012083953-A1 | INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES | LEO PHARMA A/S (DK) | 2012-06-28 | — | — | WO | claimed |
| EP-2655323-A1 | INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES | LEO LABORATORIES LIMITED (IE) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012083953-A1 | INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES | LEO PHARMA A/S (DK) | 2012-06-28 | — | — | WO | disclosed |