Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9959027 | 0.88 | IMPDH2 (0.37) | IMPDH2 | |
| SCHEMBL9959025 | 0.80 | IMPDH2 (0.32) | IMPDH2 | |
| SCHEMBL9929126 | 0.75 | IMPDH2 (0.36) | IMPDH2 | |
| SCHEMBL1425779 | 0.73 | CSF1R (0.30) | — | |
| SCHEMBL17010225 | 0.70 | IMPDH2 (0.34) | IMPDH2 | |
| SCHEMBL20240848 | 0.70 | IMPDH2 (0.37) | IMPDH2 | |
| SCHEMBL18342659 | 0.70 | — | — | |
| SCHEMBL9929116 | 0.69 | IMPDH2 (0.32) | IMPDH2 | |
| SCHEMBL26132539 | 0.68 | EGFR (0.34) | — | |
| SCHEMBL14135031 | 0.67 | TPMT (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655374-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | Incyte Corporation (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012087881-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2012-06-28 | — | — | WO | disclosed |