Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1648372 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL29024671 | 0.78 | MAPK1 (0.32) | MAPK1NFKB1NFKB2RELA | |
| Hydrochloric Acid SCHEMBL29024517 | 0.78 | MAPK1 (0.32) | MAPK1NFKB1NFKB2RELA | |
| SCHEMBL486744 | 0.72 | MAPK1 (0.34) | MAPK1 | |
| SCHEMBL3410964 | 0.71 | — | — | |
| SCHEMBL5780327 | 0.71 | — | — | |
| SCHEMBL14830055 | 0.70 | — | — | |
| SCHEMBL4670268 | 0.69 | NFKB1 (0.34) | NFKB1NFKB2RELA | |
| SCHEMBL1986795 | 0.68 | — | — | |
| SCHEMBL2635389 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010130708-A9 | BETA-LACTAMASE INHIBITORS | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2011-01-13 | — | — | WO | disclosed |