Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31410746 | 0.88 | POLB (0.37) | POLBKMT2AMRGPRX4LMNAMAPT | |
| SCHEMBL31410739 | 0.87 | NR1H4 (0.43) | POLBKMT2AMRGPRX4HSD17B10SLC7A5 | |
| SCHEMBL15777721 | 0.85 | POLB (0.36) | POLBKMT2AMRGPRX4LMNAMAPT | |
| SCHEMBL31410740 | 0.84 | KDM4E (0.40) | GABRA1GABRB2POLBKMT2AMRGPRX4 | |
| SCHEMBL28104610 | 0.83 | ALDH1A1 (0.50) | POLBKMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL31410748 | 0.82 | ALDH1A1 (0.44) | POLBKMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL951581 | 0.82 | TSHR (0.46) | GABRA1GABRB2LMNAADRA1AADRA1B | |
| SCHEMBL29196257 | 0.81 | TSHR (0.59) | POLBKMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL15110860 | 0.81 | KMT2A (0.54) | POLBKMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL23888869 | 0.80 | KMT2A (0.38) | POLBKMT2ALMNAADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010130708-A9 | BETA-LACTAMASE INHIBITORS | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2011-01-13 | — | — | WO | disclosed |