Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL99035 | 0.93 | HDAC1 (0.51) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL98704 | 0.90 | AKR1C3 (0.51) | MAPTHTTHDAC3HDAC4HDAC1 | |
| SCHEMBL101223 | 0.83 | HDAC1 (0.51) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL101623 | 0.82 | HDAC2 (0.48) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15823153 | 0.82 | HDAC1 (0.47) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28194557 | 0.82 | MAPT (0.66) | MAPTHTTHDAC3HDAC4HDAC1 | |
| SCHEMBL99215 | 0.81 | AKR1C3 (0.49) | MAPTHTTHDAC1GAAMEN1 | |
| SCHEMBL15821963 | 0.79 | AKR1C3 (0.50) | MAPTHTTHDAC3HDAC4HDAC1 | |
| SCHEMBL663300 | 0.79 | CHRM3 (0.60) | — | |
| Iodide SCHEMBL102604 | 0.78 | CHRM3 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | claimed |