SCHEMBL9963642

SCHEMBL9963642

COc1ccc(C(=O)c2ccc(C(C)=O)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.68
RAB9A P51151 2/20 0.68
HPGD P15428 2/20 0.68
RXFP1 Q9HBX9 2/20 0.68
MEN1 O00255 2/20 0.68
KMT2A Q03164 2/20 0.68
LMNA P02545 1/20 0.68
MAPK1 P28482 1/20 0.68
NPSR1 Q6W5P4 1/20 0.68
CES2 O00748 2/20 0.61
CES1 P23141 2/20 0.61
ALDH1A1 P00352 2/20 0.61
GAA P10253 1/20 0.61
TUBB4A P04350 1/20 0.59
TUBB P07437 1/20 0.59
TUBA3C P0DPH7 1/20 0.59
TUBA1B P68363 1/20 0.59
TUBA4A P68366 1/20 0.59
TUBB4B P68371 1/20 0.59
TUBB3 Q13509 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14198677 0.94 MAPT (0.73) MAPTRAB9AHPGDRXFP1MEN1
SCHEMBL12372650 0.94 MAPT (0.73) MAPTRAB9AHPGDRXFP1MEN1
SCHEMBL12372656 0.94 MAPT (0.73) MAPTRAB9AHPGDRXFP1MEN1
SCHEMBL14407940 0.94 MAPT (0.73) MAPTRAB9AHPGDRXFP1MEN1
P-Methoxy-Acetophenone SCHEMBL41285 0.93 MAPT (0.70) MAPTRAB9AHPGDRXFP1MEN1
P-Methoxy-Acetophenone SCHEMBL9835038 0.91 MAPT (0.67) MAPTRAB9AHPGDRXFP1MEN1
P-Methoxy-Acetophenone SCHEMBL27967967 0.91 MAPT (0.67) MAPTRAB9AHPGDRXFP1MEN1
P-Methoxy-Acetophenone SCHEMBL27814658 0.91 MAPT (0.67) MAPTRAB9AHPGDRXFP1MEN1
P-Methoxy-Acetophenone SCHEMBL27841741 0.91 MAPT (0.67) MAPTRAB9AHPGDRXFP1MEN1
SCHEMBL51509 0.91 RXFP1 (0.79) MAPTRAB9AHPGDRXFP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293331-B2 Metal-coated polyimide film KANEKA CORPORATION (JP) 2012-10-23 US disclosed
US-20120156388-A1 METAL-COATED POLYIMIDE FILM KANEKA CORPORATION (JP) 2012-06-21 US disclosed
US-20090281267-A1 Material for planting and use thereof KANEKA CORPORATION (JP) 2009-11-12 US disclosed
US-7267883-B2 Polyimide film and laminate having metal layer and same KANEKA CORPORATION (JP) 2007-09-11 US disclosed